Published Research

1. J Agric Food Chem. 2007 Jul 25;55(15):6032-8. Epub 2007 Jul 4. Insoluble fraction of buckwheat (Fagopyrum esculentum Moench) protein possessing cholesterol-binding properties that reduce micelle cholesterol solubility and uptake by Caco-2 cells. Metzger BT, Barnes DM, Reed JD.
2. J Agric Food Chem. 2007 Aug 8;55(16):6439-46. Epub 2007 Jul 6. Aqueous extract from Spanish black radish (Raphanus sativus L. Var. niger) induces detoxification enzymes in the HepG2 human hepatoma cell line. Hanlon PR, Webber DM, Barnes DM.
3. J Agric Food Chem. 2008 May 28;56(10):3554-60. Epub 2008 Apr 24. Purple carrot (Daucus carota L.) polyacetylenes decrease lipopolysaccharide-induced expression of inflammatory proteins in macrophage and endothelial cells. Metzger BT, Barnes DM, Reed JD.
4. J Chiropr Med. 2008 Sep;7(3):94-100. A nutritional program improved lipid profiles and weight in 28 chiropractic patients: a retrospective case series. Powell JP, Leonard JS.
5. J Med Food. 2009 Aug;12(4):854-60. A comparison of pectin, polyphenols, and phytosterols, alone or in combination, to lovastatin for reduction of serum lipids in familial hypercholesterolemic swine. Metzger BT, Barnes DM, Reed JD.
6. Journal of Functional Foods Volume 1, Issue 4, October 2009, Pages 356-365 Aqueous extract from the vegetative portion of Spanish black radish (Raphanus sativus L. var. niger) induces detoxification enzyme expression in HepG2 cells. Paul R. Hanlon, Melissa G. Robbins, Lori D. Hammon, David M. Barnes
7. J Agric Food Chem. 2009 Dec 9;57(23):11134-9. Polyacetylene diversity and bioactivity in orange market and locally grown colored carrots (Daucus carota L.). Metzger BT, Barnes DM.
8. BMC Complement Altern Med. 2009 Dec 14;9:51. Aqueous extracts from dietary supplements influence the production of inflammatory cytokines in immortalized and primary T lymphocytes. Hanlon PR, Robbins MG, Scholl C, Barnes DM.
9. J Food Sci. 2010 Aug 1;75(6):H190-9. Induction of detoxification enzymes by feeding unblanched Brussels sprouts containing active myrosinase to mice for 2 wk. Robbins MG, Hauder J, Somoza V, Eshelman BD, Barnes DM, Hanlon PR.
10. J Herbs Spices Med Plants 2010 Aug 16:106-118. Longitudinal expression of antioxidant phytochemicals in buckwheat (Fagopyrum esculentum Moench). Metzger BT, Robbins MG, Barnes DM
11. J Food Sci. 2011 Jan-Feb;76(1):C185-92. doi: 10.1111/j.1750-3841.2010.01972.x. Phytochemical composition and biological activity of 8 varieties of radish (Raphanus sativus L.) sprouts and mature taproots. Hanlon PR, Barnes DM.
12. J Food Sci. 2011 Apr;76(3):C504-11. doi: 10.1111/j.1750-3841.2011.02078.x. Epub 2011 Mar 21.Raphasatin is a more potent inducer of the detoxification enzymes than its degradation products. Scholl C, Eshelman BD, Barnes DM, Hanlon PR.
13. J Food Sci. 2011 Apr;76(3):C454-61. doi: 10.1111/j.1750-3841.2011.02105.x. Heat treatment of Brussels sprouts retains their ability to induce detoxification enzyme expression in vitro and in vivo. Robbins MG, Andersen G, Somoza V, Eshelman BD, Barnes DM, Hanlon PR.
14. Brandon T. Metzger. 2012 March 6. Chapter 10: "Carrot Bisacetylenic Oxylipins - Phytochemicals Behind the Mask of the Superfood" in Emerging Trends in Dietary Components for Preventing and Combating Disease, American Chemical Society, ACS Symposium Series Vol. 1093; 167-184.
15. Nutr Cancer. 2012 Oct;64(7):1038-4. Spanish Black Radish (Raphanus Sativus l. var. niger) Diet Enhances Clearance of DMBA and Diminishes Toxic Effects on Bone Marrow Progenitor Cells. N'jai AU, Kemp MQ, Metzger BT, Hanlon PR, Robbins M, Czuyprynski C, Barnes DM.

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