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Kava Forte                 This tablet contains Kava root extracted with 100%   Supplement Facts
                                       water, which provides an extract with a full
                                       spectrum of compounds including kavalactones.  Serving size:   1 tablet
                                                                           Servings per container:       40
                                       This product is standardized to contain 50 mg of kavalactones
                                       per tablet to ensure optimal strength and quality.      Amount per Serving  %DV  Tablets and Capsules
                                       The compounds in Kava Forte, particularly the   Kava root 7:1 water extract   455 mg  †
                                       kavalactones, work together to traditionally help:   from Piper methysticum root 3.2 g
                                       ƒ ƒ calm the nerves                 Containing kavalactones 50 mg
                                       ƒ ƒ ease the effects of temporary tension and stress  †  Daily Value (DV) not established.
                                       ƒ ƒ promote relaxation and sleep
                                                                          Other ingredients: Microcrystalline cellulose, maltodextrin,
                                       ƒ ƒ support muscle relaxation*     magnesium stearate, silicon dioxide, hypromellose, sodium starch
                                       Caution: US FDA advises that a potential risk of rare, but   glycolate and dibasic calcium phosphate dihydrate.
                                       severe, liver injury may be associated with kava-containing   Content      Product No
                                       dietary supplements. Ask a health care professional before   40 Tablets     M1345
                                       use if you have or have had liver problems, frequently use
                                       alcoholic beverages, or are taking any medication. Stop use   Suggested Use
                                       and see a doctor if you develop symptoms that may signal   1 tablet 2 – 3 times daily, or as directed.
                                       liver problems (eg unexplained fatigue, abdominal pain, loss   Educational Tools
                                                                                                       ®
                                       of appetite, fever, vomiting, dark urine, pale stools, yellow   L0329: Clinical Success Made Simple With MediHerb  Handout
                                       eyes or skin). Not for use by persons under 18 years of age, or  L0651: Kava Forte Brochure
                                       by pregnant or breastfeeding women. Not for use with   L0322: Kava Forte Handout
                                       alcoholic beverages. Excessive use, or use with products that   Product Detail Sheet available online
                                       cause drowsiness, may impair your ability to operate a
                                       vehicle or dangerous equipment. Not for prolonged use. Do
                                       not exceed recommended dose. t
                                       Additional Support
                                       ƒ ƒ Combines well with Valerian Complex tablets to promote
                                        relaxation and encourage sleep.
                                       ƒ ƒ Consider Nevaton  Forte or St John’s Wort 1.8g tablets to
                                                  ®
                                        provide a tonic for the nervous system and ease the
                                        effects of occasional stress.
                                       ƒ ƒ Combine with FemCo tablets to ease the effects of
                                        everyday tension and stress.
                                       ƒ ƒ Consider Wild Yam Complex tablets to maintain feelings of
                                        general well-being/calm the nerves.
                                       ƒ ƒ Consider Adrenal Complex tablets for adrenal support.
                                       ƒ ƒ Consider HiPep tablets to reduce occasional stomach acid
                                        secretions.
                                       ƒ ƒ Consider Nervagesic tablets to support relaxation in the
                                        nervous system and muscles.*



                                       Kava Quality Story

                                                                                    100  water
                                                                                     90  ethanol
                                                                                         standard
                                        Kava is derived from the rootstock of the sterile cultivated species   80
                                       of Piper methysticum                          70
                                       The active property of Kava has been attributed to the kavalactones, a group of   % apical  60 50
                                       structurally related lipophilic lactones. These compounds can represent 3 to 20% by   40
                                       weight of the dried rootstock, depending on the age of the plant and the specific cultivar.   30
                                       The majority of the Kava used commercially in the world is in the form of a high ethanol   20
                                       or other organic solvent extract, which extracts little more than the kavalactones and   10
                                        has reported potential hepatoxicity concerns. The Therapeutic Goods Administration   0
                                       (TGA) allows water extracted or plain unextracted root to be sold in Australia.  0  40  80  120  160
                                                                                                   Time (min)
             Kava (Piper methysticum)  Traditionally Kava beverages are prepared by chewing or pounding the root to produce a
                                       cloudy, milky mash, which is then consumed orally. It is known that extraction with   Kawain % apical average data
                                       different solvents affects the phytochemical profile of the extract.  Time  water  ethanol  standard
                                       MediHerb  investigated the difference in bioavailability of the water extract of Kava and   10  11  11  12
                                            ®
                                        the 96% ethanol extract using the Caco-2 monolayer in vitro model. The kavalactones   20  21  22  23
                                       (as kawain) were found to be potentially bioavailable as they all crossed the membrane   30  30  31  33
                                       quite readily with the exception of one kavalactone (yangonin). The water extract of   60  59  59  61
                                        Kava was only slightly less bioavailable than the ethanol extract. Therefore the clinical   90  80  81  84
                                       effect of the water extract of Kava would be similar to that of an ethanol extract.  120  87  89  91
                                                                                        150    92     95    97




                                                                              Tablets and Capsules • MediHerb Product Catalog 2018  53
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