Page 63 - 2018 SP Product Guide

Rhodiola Quality Story

Rhodiola rosea (Sedum roseum) is commonly referred to as Golden Root or Roseroot and grows in dry sandy
ground at high altitudes in the arctic regions of Europe and Asia.
The freshly cut root has a rose-like odor that has led to its botanical name and one of its common names. The root has been used for
centuries in the traditional herbalism of Russia and Scandinavia. There are however 16 common species of Rhodiola growing in the
Eurasian area. Of these, 11 have been tested in animal studies, but only R. rosea and to a far lesser extent R. crenulata have been
assessed in human trials.
Most of the Rhodiola species have been reported to contain the marker compound salidroside and this was originally used to
standardize extracts of Rhodiola rosea. After more than a decade of research, however, it was shown that the chemical composition
of R. rosea root is, in fact, different to the other species of the genus Rhodiola. Using newly developed methods of analysis, it was
Rhodiola (Rhodiola rosea) shown that R. rosea root contains three cinnamyl alcohol-vicianosides: rosavin, rosin, and rosarin that are specific to this species.
They are collectively termed rosavins. HPLC offers a ready method to differentiate true Rhodiola rosea from the other species
offered on the market. The two major rosavins found are rosavin and rosarin, with only very low quantities of rosin.

HPLC trace of Rhodiola rosea
Rosavin
Rosarin

Korean Ginseng Quality Story

Panax ginseng is a widely used and misunderstood herb. Traditionally the main root of the plant has been
preferred for clinical use.
The other parts of the plant such as the root hairs, leaves, leafstalks, etc are considered inferior and are never used clinically in the
East. However, many herb traders will sell the other plant parts as they are substantially cheaper than the main root. The major
marker compounds used to characterize Panax ginseng are the ginsenosides which occur in all parts of the plant and if you were to
only consider total ginsenosides the main root is not the highest in content. The importance is in the ratio of specific ginsenosides.
The European clinical studies were undertaken on extracts manufactured from the main root of Panax ginseng which have a
particular ratio of ginsenosides. To achieve the clinical results obtained traditionally and supported by clinical trials it is important to
use raw material from the correct plant part and the correct species. This is readily achievable using HPLC which easily distinguishes
the different preparations.
Korean Ginseng (Panax ginseng)
% Content
Rg 1 Re Rf Rg 2 Rb 1 Rc Rb 2 Rd Total
Leaves 1.078 1.524 — — 0.184 0.736 0.553 1.113 5.188
Leafstalks 0.327 0.141 — — — 0.190 — 0.107 0.765
Stem 0.292 0.070 — — — — 0.397 — 0.759
Main root 0.379 0.153 0.092 0.023 0.342 0.190 0.131 0.038 1.348
Lateral roots 0.406 0.668 0.203 0.090 0.850 0.738 0.434 0.143 3.532
Root hairs 0.376 1.512 0.150 0.249 1.351 1.349 0.780 0.381 6.148
Main root dry extract 1.4 2.1 0.6 0.6 2.9 1.9 2.4 1.5 13.4
Re

Rg1
Rd
Rb2
Rg2
Korean Ginseng leaf dry extract
Rc
Rb1
Rf
Korean Ginseng root dry extract
KOREPE
62 MediHerb Product Catalog 2018• Tablets and Capsules
®