Page 138 - 2018 SP Product Guide

Recommended Action Monitor (low level of risk). Contraindicated. Monitor (low level of risk). Monitor (very low level of risk). Avoid excessive doses of laxatives. Maintain patients on a high potassium diet. Monitor (low level of risk at normal doses). Avoid excessive doses of laxatives. Maintain patients on a high potassium diet. Care should be exercised with patients who exhibit long-term use of laxative herbs or Critical drugs should be taken at different

2 diabetics. 167 Clinical significance unclear. No effect on insulin sensitivity or beta-cell function after very high
Theoretical concern based on in vitro studies which show ginseng increases nitric oxide release from corpus
doses in newly diagnosed type 2 diabetics or those with impaired glucose tolerance. 168 Korean red ginseng
Theoretical concern based on clinically observed hypoglycemic activity of ginseng in newly diagnosed type
(2.7 g/day) reduced the requirement for insulin in about 40% of diabetics in a small uncontrolled trial. 169
No adverse effects in three trials of type 2 diabetics well controlled with diet and/or oral hypoglycemic
Clinical study with healthy volunteers (extract providing about 45 mg/day of ginsenosides). 175

potassium-losing diuretics. 1 hour, preferably more. then again, after surgery. effective. In the ideal situation the dose of the drug could be adjusted. wort and digoxin. Safety. Churchill Livingstone, USA, 2005.

German Commission E and ESCOP recommendation. 9,178 German Commission E and ESCOP recommendation. 9,178 German Commission E and ESCOP recommendation. 9,178

Basis of Concern drugs. 152,170,171 Case reports. 172-174 cavernosum tissue. 176,177 Laxative (anthraquinone-containing) herbs eg cascara (Frangula purshiana, Rhamnus purshianus), yellow dock (Rumex crispus)

Potential Interaction May potentiate hypoglycemic activity of drug. 44 May cause side effects such as headache, sleeplessness, tremor. May decrease drug level. Potentiation of drug possible. May affect activity if potassium deficiency resulting from long-term laxative abuse is present. May potentiate activity, if potassium deficiency resulting from long-term laxative abuse is present. May increase potassium depletion. Herb-Drug Interaction Chart: Gene

Hypoglycemic drugs including MAO inhibitors eg phenelzine Antiarrhythmic agents Potassium-depleting agents eg thiazide diuretics, corticosteroids, licorice root (Glycyrrhiza glabra) regular basis. in elderly patients, in pregnant women,

Drug insulin Midazolam Sildenafil Cardiac glycosides – – – – –

Herb-Drug Interaction Chart • MediHerb Product Catalog 2018 137
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