Page 141 - 2018 SP Product Guide

Recommended Action Monitor (low level of risk). Monitor (medium level of risk). Also advisable not to take simultaneously. In anemia and where iron supplementation is required, do not take simultaneously with meals or iron supplements. Monitor (very low level of risk). Monitor (low level of risk at normal doses). Monitor (medium level of risk at normal doses). Monitor (medium level of risk). Monitor (low level of risk at normal doses).

berberine by injection (reduced bilirubin serum protein binding). 119 Theoretical concern based on in vitro data (displaced bilirubin from albumin) and in animals with high dose of especially cayenne (Capsicum annuum), chamomile (Matricaria chamomilla (Matricaria recutita)), green tea (Camellia sinensis), lime flowers (Tilia cordata), milk thistle (Silybum marianum), rosemary (Rosmarinus officinalis) (See also Tannin-containing herbs) Three case reports,

Basis of Concern Herb Alone but no signs of rejection. 236 dosage. 249 Herb Alone Case report (hemorrhage during surgery). 251 (1 trial). 252 Herb and Drug the usual dose of extract was taken). 67.5 mg/day of deoxyschisandrin FF . deoxyschisandrin FF . 259 metabolism. 260,261 33.75 mg/day of deoxyschisandrin FF . 118

Potential Interaction May potentiate effect of drug on displacing bilirubin. Decreases drug levels, due to impaired absorption or increased metabolism. Inhibition of non-heme iron AA absorption. May potentiate effect of drug. May increase drug levels. May increase drug levels. May accelerate clearance from the body. May increase drug levels.

Phellodendron N Phellodendron amurense Drugs that displace the protein Polyphenol-containing Z or Flavonoid-containing herbs Immunosuppressives eg cyclosporin Saw Palmetto Serenoa repens Antiplatelet and anticoagulant Schisandra Schisandra chinensis

Drug binding of bilirubin eg phenylbutazone Iron drugs Immunosuppressives Midazolam Prescribed medication Talinolol

140 MediHerb Product Catalog 2018 • Herb-Drug Interaction Chart
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